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Departments

Research in Surgery

Research

While all divisions and sections have active research and scholarly initiatives, the department has two divisions devoted primarily to research:

As part of the University's commitment to translational research, the department is committed to innovative clinical research and technology transfer. Through the Technology Transfer Laboratory, promising advances in technology, surgical techniques and basic science observations can be developed and moved to the patient's bedside.

Research Leadership

Clinical Studies

The Department of Surgery participates in many clinical trials.

Current Studies

View active surgery clinical trials in StudyFinder, our searchable database of clinical research taking place at Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine.Clinical research is conducted in the areas or divisions of:

  • Colon and rectal surgery

  • General surgery specialties and surgical oncology

  • Minimally invasive surgery/bariatrics

  • Pediatric surgery

  • Plastic surgery

  • Thoracic surgery

  • Trauma, acute care and critical care surgery

Facilities

Learn more about facilities in the Department of Surgery.

Laboratory: Maintains a polymer fabrication lab (700 square feet), system assembly clean room (260 square feet), machine shop (1,000 square feet), electronics lab (200 square feet), mock loop test lab (630 square feet), mechanical assembly room (120 square feet) and computer-aided design room (120 square feet) in the Biomedical Research Building. Penn State Health Milton S. Hershey Medical Center maintains a 1,000-square-foot clinical Hematology, Coagulation and Thrombosis Laboratory section that also supports our research mission.

Animal: The large animal wing of the Animal Research Facility has surgery and surgical support facilities (2,000 square feet), two animal care rooms (1,250 square feet), a radiology suite, holding rooms, and a necropsy room. Office and storage space (800 square feet) are also available. The Department of Comparative Medicine includes histopathology, clinical chemistry and microbiology labs to support research. The diagnostic labs provide rapid hematology, clinical chemistry, serologic and histologic support, and diagnostic bacteriological studies, including antibiotic sensitivity testing for each species of lab animal. A staff of veterinarians trained in lab animal medicine and veterinary pathology provides professional support.

Computer: Computer support provided by Penn State includes internet access, software and license support as well as access to regional supercomputing facilities. The College of Medicine provides support for local networking and data backup. Computer-aided design tools and data acquisition systems in the Division of Applied Biomedical Engineering are PC-based. Licensed software includes Solidworks, Autodesk Simulation CFD, CONVERGE CFD, CAESES, LabView, and Matlab. Several stand-alone PC’s are available for controller software development, data acquisition and analysis, and monitoring of in vivo and in vitro experiments.

Office: Adequate office space is available for both in-person and video conferences, analysis of research data and manuscript preparation. Grant preparation support services and budget administration are available through the Department of Surgery at the College of Medicine. Statistical analysis support is available through the Division of Outcomes Research and Quality within the Department of Surgery and also in conjunction with the Department of Public Health Sciences.

Office: The faculty offices are within an office suite which contains a conference room for collaborating with other faculty that contains 533 square feet. A full-time administrative assistant that assists with scheduling and other duties is available to provide office administrative support.

Computer: The primary computing facility for the department’s faculty and staff is an integrated network of Microsoft Windows, Apple Macintosh and Sun Solaris computing platforms. Faculty and staff are equipped with Intel-based PC workstations running Microsoft Windows 7 Professional and Mac OS X. All systems on the department’s Ethernet network communicate via the TCP/IP protocol. Print services for the department are handled by several networked HP Color LaserJet Postscript-compatible laser printers with duplex capability. Common statistical and data management packages such as SAS, SPlus, Stata, StatXact, Sudaan, SPSS, Mplus, Genstat, Glim, nQuery, DBMS Copy and Minitab, as well as R, C, C++, Fortran 90 and 77 compilers with associated libraries (including IMSL Math Libraries), and other computing resources are readily available for use in statistical analysis and data management.

Laboratory: Located on the fourth floor of Biomedical Research Building, the laboratory is state-of-the-art and is well-equipped for all aspects of biochemical, molecular biology and molecular genetics research. The laboratory has a total of 1,983 square feet, in four rooms. This includes all of the standard laboratory equipment (i.e., vortexes, stirrers, pH meter, balances, etc.) and an array of molecular biology equipment, refrigerators, freezers, centrifuges, incubators and more.

Computer: Dr. Yochum has a personal computer (Macintosh iMac, with OS X) and a laser printer in his office. The laboratory has 5 additional computers (3 desktop, 2 laptop) assigned to research staff members. All computers are connected through the network, and each has access to the Internet and e-mail. Software available on all computers includes Microsoft office, Adobe photoshop, Adobe Illustrator and Graphpad Prism. The computers are also linked to our main campus at University Park. The University Park link affords access to the Biotechnology Institute, which maintains a large variety of protein and DNA analysis programs including the Galaxy pipelines used to map and analyze Next-generation sequencing libraries. The campus Information Resources Technology unit supports the campus website, which includes departmental and programmatic websites. The University computing center supports the email system, financial management system, and the interactive videoconferencing network for the 25 Penn State campuses. The Harrell Library at the College of Medicine is part of the University computing network.

Office: Dr. Yochum has a private office (100 sq. ft.) within the laboratory that is equipped with a desk, a telephone, a small conference table, a white-board, filing cabinets, bookshelves and standard office equipment. The room has high-speed, hard-wired internet access, and access to the internet through the wireless network. The office provides the necessary space for meeting with research team members, analyzing and interpreting results, and preparing manuscripts for publication. The lab office is down the hall from the main Department of Surgery, Division of Colon and Rectal Surgery office suite where the PI has access to color printers, a fax machine and copiers. The secretarial and administrative support team for the department is also located in the main office. The PI has full access to institute secretarial support.

Laboratory: The well-equipped, 2,000-square-foot laboratory has 8 rooms: adjoining 90-square-foot technician’s office, 90-square-foot fellow’s office, 90-square-foot microscope room, three 120-square-foot cell culture rooms, and an 80-square-foot bioprinting room. The laboratory is housed with multiple computers for use by lab personnel.

Office: Dr. Ravnic has a separate office within the Division of Plastic Surgery academic suite. The Division has a library/conference room with generous space for group meetings between key personnel. The Department provides secretarial assistance, office supplies and telephone.

Laboratory: A 3D printing program has been established within the Department of Surgery. The 3D printer allows for the rapid conversion of innovative ideas into working prototypes for experimental use in just a few hours. Working in concert with Radiology’s “3D Recon enhanced patient imaging technologies,” anatomical models can first be visualized in 3D and then quickly built to hold in your hands for use as a surgical planning tool, clinical decision adjunct, surgical practice tool or classroom aide.

The Fortus 400mc 3-D printer is located on the fourth floor in the Dept of Surgery research labs. Cost for using the printer is based on an hourly rate with discounts for larger print times.

For details, email 3DPrint@pennstatehealth.psu.edu.

National Surgical Quality Improvement Program (NSQIP)

The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) is a nationally validated, risk-adjusted, outcomes-based program designed to measure and improve the quality of surgical care. It uses data gathered from medical charts by clinically trained personnel and includes demographics, preoperative risk factors, and intraoperative through 30-day postoperative outcomes data.Penn State Health Milton S. Hershey Medical Center currently participates in three ACS NSQIP programs:

  • Adult NSQIP Procedure Targeted Option

    – Collects data on high-risk, high-volume surgeries which include colectomy, proctectomy, appendectomy, pancreatectomy, hepatectomy, esophagectomy, lung resection, cystectomy, prostatectomy, nephrectomy, breast reconstruction and muscle flaps.

  • Pediatric NSQIP

    – Measures the quality of surgical care for children younger than 18 across multiple specialties.

  • Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP)

    – A joint program of the ACS and the American Society for Metabolic and Bariatric Surgery (ASMBS), established in 2012 for the purposes of reporting from a national registry, providing accreditation and setting standards for quality care in bariatric surgery.

ACS NSQIP provides data reports in several formats:

  • Semiannual reports:

    A comprehensive risk-adjusted report released twice a year using hierarchical modeling reported as odds ratios (OR) for each participating hospital.

  • Online reports:

    Continuously updated site-specific reports comparing our unadjusted data to national averages.

  • Participant Use Data File (PUF):

    An aggregate file containing national HIPAA-compliant patient level data, for the purpose of data analysis by researchers to improve the quality of surgical patient care.

Research Using NSQIP Data

If you are a current Penn State Health or visiting student, resident, intern or doctor and would like additional information about NSQIP or are considering writing a research article using Penn State Health or National NSQIP data, please email Pamela Huggins at phuggins@pennstatehealth.psu.edu for a data request form.

Contact Us

To speak to someone about surgery research and collaborations, please call 717-531-5810 or email Heidi Payne at hpayne@pennstatehealth.psu.edu.