Matthew Moyer, MS, MD
Professor, Medicine
Biography
Dr. Moyer is a full professor at Penn State College of Medicine and Penn State Health in the Division of Gastroenterology and a member of the Penn State Cancer Institute.
He concentrates both clinically and in research on interventional endoscopy, gastrointestinal cancer and the development of innovative endoscopic techniques, and is recognized internationally as an expert on pancreatic cysts and EUS-guided chemoablation. Dr. Moyer has authored over 90 publications, regularly speaks at international conferences, and has been a co- or principal investigator on multiple clinical trials including the principal investigator of the NIH-funded CHARM II multi-center randomized clinical trial. His clinical practice centers on pancreatic and biliary disease, inflammatory bowel disease and interventional endoscopy including ERCP, EUS, EUS-guided interventional techniques, EMR/ESD and EUS-guided tumor ablation.
Dr. Moyer has received multiple awards including the recognition of his commitment to graduate medical education and trainee mentorship.
Dr. Moyer lives with his family on the family farm just outside of Hershey and regularly staffs the free medical clinic of the Bethesda Mission in Harrisburg.
Research Highlights
![[object Object]](https://images.ctfassets.net/u5e6iuf5dlnc/1ODyQdUXaA9kaA0iql8Pz4/add96ac72e3ad24dc7e85ca4ab0dfef5/moyer-lab-figure-1.jpg)
![[object Object]](https://images.ctfassets.net/u5e6iuf5dlnc/7ndOHehtxcGOTOzzyDBjVn/3c798709cb80c8f6d4bd84b2c2628008/Moyer-lab-figure-2jpg.jpg)
![[object Object]](https://images.ctfassets.net/u5e6iuf5dlnc/4j3cDgEiebRILROCT8K0Li/d261de1b260d8ffb262a6c2bc6efca33/Chimera-poster-moyer-lab-scaled.jpg)
The Chimera Project is a joint effort with Penn State Bioengineering to develop a minimally invasive EUS-guided ablation device for solid abdominal and mediastinal tumors.
The alcohol-free, EUS-guided, cyst ablation process: The FNA needle is introduced into the center of the cystic lesion, followed by near complete aspiration of mucinous fluid from all compartments, leaving a small rim of fluid around the needle tip to prevent damaging the cyst wall. This is followed subsequently filling the cyst with an equal volume of the CHARM chemotherapy ablation admixture.
Before and after MRI and MRCP images of a patient with a 3.6cm mucinous (precancerous) pancreatic cyst participating in the CHARM Trial. Images on the right show complete resolution of the cyst after EUS-guided chemoablation using the CHARM Protocol.